Antibiotic-associated diarrhea (AAD)

Taking into account the data available as of now, AAD can occur with frequency of up to 39% at people, who receive antibiotics. At the same time, diarrhea occurs approximately at 10-25% of patients, who took amoxicillin with clavulanate, at 15-20% of cefixime.(1)

Inulin reduced the negative effects when the beta-lactam antibiotic ampicillin was added after 30 hours, completely restoring the metabolic and taxonomic functions and the composition of representatives of the normal flora.(2)

(1). Yassin S.F., MD; Young-Fadok T.M., MD, MS et al. Clostridium difficile–Associated Diarrhea and Colitis. Mayo Clin Proc. (July 2001). Vol 76 p. 725-730

(2). Johnson LP, Walton GE, Psichas A, Frost GS, Gibson GR, Barraclough TG. Prebiotics Modulate the Effects of Antibiotics on Gut Microbial Diversity and Functioning in Vitro. Nutrients. 2015;7(6):4480-97.